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CTNNA2 抗体 (C-Term)

CTNNA2 适用: 人 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6261087
发货至: 中国
  • 抗原 See all CTNNA2 抗体
    CTNNA2 (Catenin (Cadherin-Associated Protein), alpha 2 (CTNNA2))
    抗原表位
    • 5
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    C-Term
    适用
    • 31
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    宿主
    • 30
    • 2
    克隆类型
    • 31
    多克隆
    标记
    • 15
    • 2
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    This CTNNA2 antibody is un-conjugated
    应用范围
    • 14
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    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    CTNNA1/CTNNA2 Antibody detects endogenous levels of total CTNNA1/CTNNA2.
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human CTNNA1/CTNNA2, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product CTNNA2 Primary Antibody
  • 应用备注
    WB 1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    CTNNA2 (Catenin (Cadherin-Associated Protein), alpha 2 (CTNNA2))
    别名
    CTNNA1,CTNNA2 (CTNNA2 产品)
    别名
    AI481747 antibody, Catna antibody, Catna2 antibody, cdf antibody, chp antibody, CAP-R antibody, CAPR antibody, CT114 antibody, CTNR antibody, CTNNA1 antibody, bZ1H10.1 antibody, catna2l antibody, im:5410539 antibody, si:rp71-1h10.1 antibody, catenin alpha 2 antibody, catenin (cadherin associated protein), alpha 2 antibody, catenin (cadherin-associated protein), alpha 2 antibody, catenin alpha 2 L homeolog antibody, ctnna2 antibody, CTNNA2 antibody, Ctnna2 antibody, ctnna2.L antibody
    背景

    Description: Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.

    Gene: CTNNA1

    分子量
    100kDa
    基因ID
    1495, 1496
    UniProt
    P35221, P26232
    途径
    Regulation of Muscle Cell Differentiation
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