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CTH 抗体 (N-Term)

This anti-CTH antibody is a 兔 多克隆 antibody detecting CTH in WB, IHC 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN6261082
发货至: 中国

Quick Overview for CTH 抗体 (N-Term) (ABIN6261082)

抗原

See all CTH 抗体
CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

适用

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  • 1
人, 小鼠

宿主

  • 59
  • 12

克隆类型

  • 58
  • 13
多克隆

标记

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  • 1
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This CTH antibody is un-conjugated

应用范围

  • 55
  • 25
  • 14
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  • 12
  • 8
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • 抗原表位

    • 13
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term

    特异性

    CTH Antibody detects endogenous levels of total CTH.

    预测反应

    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human CTH, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    CTH (Cystathionase (Cystathionine gamma-Lyase) (CTH))

    别名

    CTH

    背景

    Description: Catalyzes the last step in the trans-sulfuration pathway from methionine to cysteine. Has broad substrate specificity. Converts cystathionine to cysteine, ammonia and 2-oxobutanoate. Converts two cysteine molecules to lanthionine and hydrogen sulfide. Can also accept homocysteine as substrate. Specificity depends on the levels of the endogenous substrates. Generates the endogenous signaling molecule hydrogen sulfide (H2S), and so contributes to the regulation of blood pressure. Acts as a cysteine-protein sulfhydrase by mediating sulfhydration of target proteins: sulfhydration consists of converting -SH groups into -SSH on specific cysteine residues of target proteins such as GAPDH, PTPN1 and NF-kappa-B subunit RELA, thereby regulating their function.

    Gene: CTH

    分子量

    45 kDa

    基因ID

    1491

    UniProt

    P32929

    途径

    ER-Nucleus Signaling, Warburg Effect
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