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COLEC12 抗体 (C-Term)

The 兔 多克隆 anti-COLEC12 antibody (ABIN6260935) specifically detects COLEC12 in WB, ELISA 和 IHC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6260935
发货至: 中国
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Quick Overview for COLEC12 抗体 (C-Term) (ABIN6260935)

抗原

See all COLEC12 抗体
COLEC12 (Collectin Sub-Family Member 12 (COLEC12))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

  • 31
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多克隆

标记

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This COLEC12 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    特异性

    COLEC12 Antibody detects endogenous levels of total COLEC12.

    预测反应

    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human COLEC12, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    COLEC12 (Collectin Sub-Family Member 12 (COLEC12))

    别名

    COLEC12

    背景

    Description: Scavenger receptor that displays several functions associated with host defense. Promotes binding and phagocytosis of Gram-positive, Gram-negative bacteria and yeast. Mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells. Binds to several carbohydrates including Gal-type ligands, D-galactose, L- and D-fucose, GalNAc, T and Tn antigens in a calcium-dependent manner and internalizes specifically GalNAc in nurse-like cells. Binds also to sialyl Lewis X or a trisaccharide and asialo-orosomucoid (ASOR). May also play a role in the clearance of amyloid-beta in Alzheimer disease.

    Gene: COLEC12

    分子量

    82 kDa

    基因ID

    81035

    UniProt

    Q5KU26

    途径

    Activation of Innate immune Response
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