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Cofilin 抗体 (N-Term)

This 兔多克隆 antibody specifically detects Cofilin in WB, ELISA, IF 和 ICC. It exhibits reactivity toward 人, 小鼠和大鼠.

Western blot analysis of Cofilin expression in COLO205 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. (Cofilin 抗体 (N-Term))

IF/ICC

2 images

产品编号 ABIN6260927

发货至: 中国

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Quick Overview for Cofilin 抗体 (N-Term) (ABIN6260927)

抗原

See all Cofilin (CFL1) 抗体

Cofilin (CFL1) (Cofilin 1 (CFL1))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This Cofilin antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Discover our top product CFL1 Primary Antibody

抗原表位
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N-Term

特异性

Cofilin Antibody detects endogenous levels of total Cofilin.

预测反应

Pig,Bovine,Horse,Sheep,Dog

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human Cofilin, corresponding to a region within N-terminal amino acids.

亚型

IgG
anti-Cofilin 1 (CFL1) (AA 1-166) antibody
CFL1 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1A1 unconjugated

anti-Cofilin 1 (CFL1) antibody
KO Validated CFL1 适用: 人 WB, IF, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Cofilin 1 (CFL1) (AA 3-161) antibody
CFL1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Cofilin 1 (CFL1) (pSer3) antibody
CFL1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cofilin 1 (CFL1) (AA 1-100) antibody
CFL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Cofilin 1 (CFL1) (AA 2-166) antibody
CFL1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, IF, ICC, FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Cofilin 1 (CFL1) (AA 70-98) antibody
CFL1 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB23947 unconjugated

anti-Cofilin 1 (CFL1) (AA 4-144) antibody
CFL1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Cofilin 1 (CFL1) (pSer3) antibody
CFL1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Cofilin 1 (CFL1) (AA 1-166) antibody
CFL1 适用: 人 WB, IHC, ELISA, IHC (p) 宿主: 小鼠 Monoclonal AT1C1 unconjugated

应用备注

WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

Cofilin (CFL1) (Cofilin 1 (CFL1))

别名

CFL1

背景

Description: Binds to F-actin and exhibits  pH -sensitive F-actin depolymerizing activity. Regulates actin cytoskeleton dynamics. Important for normal progress through mitosis and normal cytokinesis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required for the up-regulation of atypical chemokine receptor ACKR2 from endosomal compartment to cell membrane, increasing its efficiency in chemokine uptake and degradation (PubMed:11812157, PubMed:15580268, PubMed:21834987, PubMed:23633677). Required for neural tube morphogenesis and neural crest cell migration (By similarity).
Gene: CFL1

分子量

19kDa

基因ID

1072

UniProt

P23528

途径

Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events