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CNDP2 抗体 (C-Term)

The 兔 多克隆 anti-CNDP2 antibody is suitable to detect CNDP2 in samples from 人, 小鼠 和 大鼠. It has been validated for WB 和 ELISA.
产品编号 ABIN6260907
发货至: 中国
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Quick Overview for CNDP2 抗体 (C-Term) (ABIN6260907)

抗原

See all CNDP2 抗体
CNDP2 (CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2))

适用

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人, 小鼠, 大鼠

宿主

  • 48
  • 11

克隆类型

  • 51
  • 8
多克隆

标记

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This CNDP2 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA
  • 抗原表位

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    C-Term

    特异性

    CNDP2 Antibody detects endogenous levels of total CNDP2.

    预测反应

    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human CNDP2, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    CNDP2 (CNDP Dipeptidase 2 (Metallopeptidase M20 Family) (CNDP2))

    别名

    CNDP2

    背景

    Description: Hydrolyzes a variety of dipeptides including L-carnosine but has a strong preference for Cys-Gly (PubMed:19346245). Acts as a functional tumor suppressor in gastric cancer via activation of the mitogen-activated protein kinase (MAPK) pathway. An elevated level of CNDP2 activates the p38 and JNK MAPK pathways to induce cell apoptosis, and a lower level of CNDP2 activates the ERK MAPK pathway to promote cell proliferation (PubMed:24395568). Isoform 2 may play a role as tumor suppressor in hepatocellular carcinoma (HCC) cells (PubMed:17121880). Catalyzes the production of N-lactoyl-amino acids from lactate and amino acids by reverse proteolysis (PubMed:25964343).

    Gene: CNDP2

    分子量

    53kDa

    基因ID

    55748

    UniProt

    Q96KP4
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