Calsyntenin 1 抗体 (C-Term)
Quick Overview for Calsyntenin 1 抗体 (C-Term) (ABIN6260898)
抗原
See all Calsyntenin 1 (CLSTN1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
特异性
- CLSTN1 Antibody detects endogenous levels of total CLSTN1.
-
预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Dog,Chicken
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human CLSTN1, corresponding to a region within C-terminal amino acids.
-
亚型
- IgG
-
-
anti-Calsyntenin 1 (CLSTN1) (AA 35-84) antibody
CLSTN1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 马, 兔, 斑马鱼, Bat, 猴, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Calsyntenin 1 (CLSTN1) (AA 1-971) antibodyCLSTN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Calsyntenin 1 (CLSTN1) (AA 29-350) antibodyCLSTN1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Calsyntenin 1 (CLSTN1) antibodyKD Validated CLSTN1 适用: 人, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Monoclonal unconjugated Recombinant Antibody
-
-
应用备注
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- Calsyntenin 1 (CLSTN1)
-
别名
- CLSTN1
-
背景
-
Description: Induces KLC1 association with vesicles and functions as a cargo in axonal anterograde transport. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation. In complex with APBA2 and C99, a C-terminal APP fragment, abolishes C99 interaction with PSEN1 and thus APP C99 cleavage by gamma-secretase, most probably through stabilization of the direct interaction between APBA2 and APP. The intracellular fragment AlcICD suppresses APBB1-dependent transactivation stimulated by APP C-terminal intracellular fragment (AICD), most probably by competing with AICD for APBB1-binding. May modulate calcium-mediated postsynaptic signals (By similarity).
Gene: CLSTN1
-
分子量
- 110 kDa
-
基因ID
- 22883
-
UniProt
- O94985
抗原
-
