SH3KBP1 抗体 (N-Term)
Quick Overview for SH3KBP1 抗体 (N-Term) (ABIN6260842)
抗原
See all SH3KBP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- CIN85 Antibody detects endogenous levels of total CIN85.
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预测反应
- Pig,Zebrafish,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human CIN85, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-SH3-Domain Kinase Binding Protein 1 (SH3KBP1) antibody
SH3KBP1 适用: 人, 大鼠, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SH3-Domain Kinase Binding Protein 1 (SH3KBP1) (AA 224-308) antibodySH3KBP1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1F11 unconjugated
anti-SH3-Domain Kinase Binding Protein 1 (SH3KBP1) (AA 1-665) antibodySH3KBP1 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-SH3-Domain Kinase Binding Protein 1 (SH3KBP1) (AA 107-156) antibodySH3KBP1 适用: 人, 大鼠, 小鼠, 兔, Cow, 犬, 豚鼠, 马, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-SH3-Domain Kinase Binding Protein 1 (SH3KBP1) (N-Term) antibodySH3KBP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SH3-Domain Kinase Binding Protein 1 (SH3KBP1) (N-Term) antibodySH3KBP1 适用: 人, 大鼠, 小鼠, 兔, Cow, 犬, 豚鼠, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- SH3KBP1 (SH3-Domain Kinase Binding Protein 1 (SH3KBP1))
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别名
- SH3KBP1
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背景
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Description: Adapter protein involved in regulating diverse signal transduction pathways. Involved in the regulation of endocytosis and lysosomal degradation of ligand-induced receptor tyrosine kinases, including EGFR and MET/hepatocyte growth factor receptor, through an association with CBL and endophilins. The association with CBL, and thus the receptor internalization, may inhibited by an interaction with PDCD6IP and/or SPRY2. Involved in regulation of ligand-dependent endocytosis of the IgE receptor. Attenuates phosphatidylinositol 3-kinase activity by interaction with its regulatory subunit (By similarity). May be involved in regulation of cell adhesion, promotes the interaction between TTK2B and PDCD6IP. May be involved in the regulation of cellular stress response via the MAPK pathways through its interaction with MAP3K4. Is involved in modulation of tumor necrosis factor mediated apoptosis. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration.
Gene: SH3KBP1
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分子量
- 85 kDa
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基因ID
- 30011
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UniProt
- Q96B97
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途径
- EGFR Signaling Pathway, EGFR Downregulation
抗原
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