CHD5 抗体 (Internal Region)
Quick Overview for CHD5 抗体 (Internal Region) (ABIN6260796)
抗原
See all CHD5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- CHD5 Antibody detects endogenous levels of total CHD5.
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预测反应
- Pig,Bovine,Horse,Sheep,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human CHD5, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (AA 1600-1699) antibody
CHD5 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (C-Term) antibodyCHD5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (Internal Region) antibodyVerified CHD5 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (C-Term) antibodyCHD5 适用: 人, 小鼠 WB, IF, ICC 宿主: 大鼠 Monoclonal 5A10 unconjugated
anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (AA 64-98) antibodyCHD5 适用: 人 WB 宿主: 兔 Polyclonal RB54755 unconjugated
anti-Chromodomain Helicase DNA Binding Protein 5 (CHD5) (AA 712-896) antibodyCHD5 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IF/ICC 1:200-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- CHD5 (Chromodomain Helicase DNA Binding Protein 5 (CHD5))
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别名
- CHD5
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背景
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Description: Chromatin-remodeling protein that binds DNA through histones and regulates gene transcription. May specifically recognize and bind trimethylated 'Lys-27' (H3K27me3) and non-methylated 'Lys-4' of histone H3. Plays a role in the development of the nervous system by activating the expression of genes promoting neuron terminal differentiation. In parallel, it may also positively regulate the trimethylation of histone H3 at 'Lys-27' thereby specifically repressing genes that promote the differentiation into non-neuronal cell lineages. Tumor suppressor, it regulates the expression of genes involved in cell proliferation and differentiation. Downstream activated genes may include CDKN2A that positively regulates the p53/TP53 pathway, which in turn, prevents cell proliferation. In spermatogenesis, it probably regulates histone hyperacetylation and the replacement of histones by transition proteins in chromatin, a crucial step in the condensation of spermatid chromatin and the production of functional spermatozoa.
Gene: CHD5
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分子量
- 223 kDa
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基因ID
- 26038
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UniProt
- Q8TDI0
抗原
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