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CENPA 抗体 (N-Term)

The 兔多克隆 anti-CENPA antibody is suitable to detect CENPA in samples from 人. It has been validated for WB 和 ELISA.

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产品编号 ABIN6260751

发货至: 中国

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Quick Overview for CENPA 抗体 (N-Term) (ABIN6260751)

抗原

See all CENPA 抗体

CENPA (Centromere Protein A (CENPA))

适用

人

宿主

兔

克隆类型

多克隆

标记

This CENPA antibody is un-conjugated

应用范围

Western Blotting (WB), ELISA

Discover our top product CENPA Primary Antibody

抗原表位
17

7

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3

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2

1

1

1

1

1

1

1

1

1

1

1

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1

1

1

1
N-Term

特异性

CENPA Antibody detects endogenous levels of total CENPA.

预测反应

Bovine,Rabbit,Dog

纯化方法

The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

免疫原

A synthesized peptide derived from human CENPA, corresponding to a region within N-terminal amino acids.

亚型

IgG
anti-Centromere Protein A (CENPA) (pSer16), (pSer18) antibody
CENPA 适用: 人 WB, IF, ICC, DB 宿主: 兔 Polyclonal unconjugated

anti-Centromere Protein A (CENPA) (N-Term) antibody
CENPA 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Centromere Protein A (CENPA) (AA 1-100) antibody
CENPA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-Centromere Protein A (CENPA) antibody
KD Validated CENPA 适用: 人 WB 宿主: 兔 Monoclonal 25GB95 unconjugated Recombinant Antibody

anti-Centromere Protein A (CENPA) antibody
CENPA 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 5A7-2E11 unconjugated

anti-Centromere Protein A (CENPA) antibody (HRP)
CENPA 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 5A7-2E11 HRP

anti-Centromere Protein A (CENPA) antibody (FITC)
CENPA 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 5A7-2E11 FITC

anti-Centromere Protein A (CENPA) antibody (Biotin)
CENPA 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 5A7-2E11 Biotin

anti-Centromere Protein A (CENPA) antibody (PE)
CENPA 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 5A7-2E11 PE

anti-Centromere Protein A (CENPA) antibody (PerCP)
CENPA 适用: 人 WB, IF, ICC 宿主: 小鼠 Monoclonal 5A7-2E11 PerCP

应用备注

WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

限制

仅限研究用
状态

Liquid

浓度

1 mg/mL

缓冲液

Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20 °C. Stable for 12 months from date of receipt.

有效期

12 months
抗原

CENPA (Centromere Protein A (CENPA))

别名

CENPA

背景

Description: Histone H3-like nucleosomal protein that is specifically found in centromeric nucleosomes (PubMed:7962047, PubMed:9024683, PubMed:11756469, PubMed:14667408, PubMed:15702419, PubMed:15475964, PubMed:15282608, PubMed:17651496, PubMed:19114591, PubMed:27499292, PubMed:20739937). Replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore (PubMed:18072184). The presence of CENPA subtly modifies the nucleosome structure and the way DNA is wrapped around the nucleosome and gives rise to protruding DNA ends that are less well-ordered and rigid compared to nucleosomes containing histone H3 (PubMed:27499292, PubMed:26878239). May serve as an epigenetic mark that propagates centromere identity through replication and cell division (PubMed:15475964, PubMed:15282608, PubMed:26878239, PubMed:20739937, PubMed:21478274). Required for recruitment and assembly of kinetochore proteins, and as a consequence required for progress through mitosis, chromosome segregation and cytokinesis (PubMed:11756469, PubMed:14667408, PubMed:18072184, PubMed:23818633, PubMed:25556658, PubMed:27499292).
Gene: CENPA

分子量

16 kDa

基因ID

1058

UniProt

P49450

途径

Chromatin Binding, Maintenance of Protein Location