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CDK3 抗体 (C-Term)

This anti-CDK3 antibody is a 兔 多克隆 antibody detecting CDK3 in WB, ELISA, ICC 和 IF. Suitable for 人 和 小鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6260712
发货至: 中国

Quick Overview for CDK3 抗体 (C-Term) (ABIN6260712)

抗原

See all CDK3 抗体
CDK3 (Cyclin-Dependent Kinase 3 (CDK3))

适用

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人, 小鼠

宿主

  • 53
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克隆类型

  • 53
  • 1
多克隆

标记

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This CDK3 antibody is un-conjugated

应用范围

  • 36
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Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

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    C-Term

    特异性

    CDK3 Antibody detects endogenous levels of total CDK3.

    预测反应

    Pig,Bovine,Sheep,Rabbit

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human CDK3, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • Wang, Xi, Sun, Zhang, Jiang, He, Li: "CDK3 is a major target of miR-150 in cell proliferation and anti-cancer effect." in: Experimental and molecular pathology, Vol. 102, Issue 2, pp. 181-190, (2017) (PubMed).

  • 抗原

    CDK3 (Cyclin-Dependent Kinase 3 (CDK3))

    别名

    CDK3

    背景

    Description: Serine/threonine-protein kinase that plays a critical role in the control of the eukaryotic cell cycle, involved in G0-G1 and G1-S cell cycle transitions. Interacts with CCNC/cyclin-C during interphase. Phosphorylates histone H1, ATF1, RB1 and CABLES1. ATF1 phosphorylation triggers ATF1 transactivation and transcriptional activities, and promotes cell proliferation and transformation. CDK3/cyclin-C mediated RB1 phosphorylation is required for G0-G1 transition. Promotes G1-S transition probably by contributing to the activation of E2F1, E2F2 and E2F3 in a RB1-independent manner.

    Gene: CDK3

    分子量

    35 kDa

    基因ID

    1018

    UniProt

    Q00526

    途径

    Cell Division Cycle
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