CDK13 抗体 (Internal Region)
Quick Overview for CDK13 抗体 (Internal Region) (ABIN6260604)
抗原
See all CDK13 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- CD2L5 Antibody detects endogenous levels of total CD2L5.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human CD2L5, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Cyclin-Dependent Kinase 13 (CDK13) (AA 1-324) antibody
CDK13 适用: 人 ELISA, WB, IF 宿主: 小鼠 Monoclonal 1B3-1B11 unconjugated
anti-Cyclin-Dependent Kinase 13 (CDK13) (AA 1-90) antibodyCDK13 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3G1 unconjugated
anti-Cyclin-Dependent Kinase 13 (CDK13) (AA 1-170) antibodyCDK13 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 13 (CDK13) antibodyCDK13 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- CDK13 (Cyclin-Dependent Kinase 13 (CDK13))
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别名
- CDK13
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背景
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Description: Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at 'Lys-50' and 'Lys-51', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.
Gene: CDK13
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分子量
- 165 kDa
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基因ID
- 8621
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UniProt
- Q14004
抗原
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