CD22 抗体
Quick Overview for CD22 抗体 (ABIN6260592)
抗原
See all CD22 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- CD22 Antibody detects endogenous levels of total CD22
-
交叉反应
- 人
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human CD22
-
亚型
- IgG
-
-
-
-
应用备注
- WB 1:1000-3000, IF/ICC 1:100-1:500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
-
有效期
- 12 months
-
-
- CD22 (CD22 Molecule (CD22))
-
别名
- CD22
-
背景
-
Description: Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins, one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.
Gene: CD22
-
分子量
- 95kDa
-
基因ID
- 933
-
UniProt
- P20273
抗原
-