CCDC99 抗体 (C-Term)
-
- 抗原 See all CCDC99 抗体
- CCDC99 (Coiled-Coil Domain Containing 99 (CCDC99))
-
抗原表位
- C-Term
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CCDC99 antibody is un-conjugated
-
应用范围
- ELISA, Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 特异性
- CCDC99 Antibody detects endogenous levels of total CCDC99.
- 预测反应
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human CCDC99, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product CCDC99 Primary Antibody
-
anti-Coiled-Coil Domain Containing 99 (CCDC99) (AA 1-605) antibody
CCDC99 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-Coiled-Coil Domain Containing 99 (CCDC99) (AA 1-300) antibodyCCDC99 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 99 (CCDC99) (AA 401-500) antibodyCCDC99 适用: 大鼠 ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 99 (CCDC99) (C-Term) antibodyCCDC99 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 99 (CCDC99) antibodyCCDC99 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 99 (CCDC99) (AA 1-605) antibodyCCDC99 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 99 (CCDC99) (AA 459-488), (C-Term) antibodyCCDC99 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33449 unconjugated
-
- 应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- CCDC99 (Coiled-Coil Domain Containing 99 (CCDC99))
- 别名
- SPDL1 (CCDC99 产品)
- 别名
- CCDC99 antibody, CG15415 antibody, Dmel\\CG15415 antibody, SPINDLY antibody, ccdc99 antibody, 1700018I02Rik antibody, 2600001J17Rik antibody, 2810049B11Rik antibody, AA409762 antibody, Ccdc99 antibody, RGD1306908 antibody, ccdc99-a antibody, ccdc99-b antibody, spdl1-a antibody, spdl1-b antibody, spdl1 antibody, spindle apparatus coiled-coil protein 1 antibody, CG15415 gene product from transcript CG15415-RB antibody, Tetratricopeptide repeat (TPR)-like superfamily protein antibody, spindle apparatus coiled-coil protein 1 L homeolog antibody, spindle apparatus coiled-coil protein 1 S homeolog antibody, SPDL1 antibody, Spindly antibody, SPY antibody, spdl1 antibody, Spdl1 antibody, spdl1.L antibody, spdl1.S antibody
- 背景
-
Description: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment (PubMed:17576797, PubMed:19468067). Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (PubMed:25035494).
Gene: SPDL1
- 分子量
- 70kDa
- 基因ID
- 54908
- UniProt
- Q96EA4
-
