CCDC99 抗体 (C-Term)
Quick Overview for CCDC99 抗体 (C-Term) (ABIN6260531)
抗原
See all CCDC99 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- CCDC99 Antibody detects endogenous levels of total CCDC99.
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预测反应
- Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human CCDC99, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Coiled-Coil Domain Containing 99 (CCDC99) (AA 1-605) antibody
CCDC99 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2F4 unconjugated
anti-Coiled-Coil Domain Containing 99 (CCDC99) (AA 1-300) antibodyCCDC99 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 99 (CCDC99) (AA 401-500) antibodyCCDC99 适用: 大鼠 ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 99 (CCDC99) (C-Term) antibodyCCDC99 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 99 (CCDC99) antibodyCCDC99 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 99 (CCDC99) (AA 1-605) antibodyCCDC99 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 99 (CCDC99) (AA 459-488), (C-Term) antibodyCCDC99 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33449 unconjugated
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应用备注
- WB 1:500-1:2000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- CCDC99 (Coiled-Coil Domain Containing 99 (CCDC99))
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别名
- SPDL1
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背景
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Description: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment (PubMed:17576797, PubMed:19468067). Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facilitates the interaction between dynein and dynactin and activates dynein processivity (the ability to move along a microtubule for a long distance without falling off the track) (PubMed:25035494).
Gene: SPDL1
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分子量
- 70kDa
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基因ID
- 54908
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UniProt
- Q96EA4
抗原
-
