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CBX2 抗体 (Internal Region)

This anti-CBX2 antibody is a 兔 多克隆 antibody detecting CBX2 in WB 和 ELISA. Suitable for 人 和 小鼠.
产品编号 ABIN6260519
发货至: 中国

Quick Overview for CBX2 抗体 (Internal Region) (ABIN6260519)

抗原

See all CBX2 抗体
CBX2 (Chromobox Homolog 2 (CBX2))

适用

  • 60
  • 27
  • 5
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
人, 小鼠

宿主

  • 51
  • 7
  • 2

克隆类型

  • 44
  • 15
  • 1
多克隆

标记

  • 38
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This CBX2 antibody is un-conjugated

应用范围

  • 39
  • 35
  • 8
  • 6
  • 5
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 8
    • 7
    • 7
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region

    特异性

    CBX2 Antibody detects endogenous levels of total CBX2.

    预测反应

    Pig,Bovine,Sheep,Rabbit

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human CBX2, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    CBX2 (Chromobox Homolog 2 (CBX2))

    别名

    CBX2

    背景

    Description: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (PubMed:21282530). PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (PubMed:21282530). Binds to histone H3 trimethylated at 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3) (By similarity). Plays a role in the lineage differentiation of the germ layers in embryonic development (By similarity). Involved in sexual development, acting as activator of NR5A1 expression (PubMed:19361780).

    Gene: CBX2

    分子量

    56 kDa

    基因ID

    84733

    UniProt

    Q14781
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