CaMK2 alpha/delta 抗体
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北京 101111
Quick Overview for CaMK2 alpha/delta 抗体 (ABIN6260427)
抗原
适用
宿主
克隆类型
标记
应用范围
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特异性
- CaMK2 alpha/delta Antibody detects endogenous levels of total CaMK2 alpha/delta
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human CaMK2 alpha/delta
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亚型
- IgG
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anti-CaMK2 alpha/delta (AA 256-305) antibody
适用: 人, 小鼠, 大鼠 IF, IHC, WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CaMK2 alpha/delta (Center) antibody适用: 人, 小鼠, 大鼠, 小鸡, Cow, Pig, 绵羊 IF, IHC, WB, IC 宿主: 兔 Polyclonal unconjugated
anti-CaMK2 alpha/delta (pSer286) antibody适用: 人, 小鼠, 大鼠, 小鸡, Cow, Pig, 猴, 兔 IF, IHC, WB, IC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
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有效期
- 12 months
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: "Inhibition of Acid Sensing Ion Channel 3 Aggravates Seizures by Regulating NMDAR Function." in: Neurochemical research, (2018) (PubMed).
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: "Inhibition of Acid Sensing Ion Channel 3 Aggravates Seizures by Regulating NMDAR Function." in: Neurochemical research, (2018) (PubMed).
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- CaMK2 alpha/delta
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背景
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Description: CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity). Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378). Activates FOXO3 transcriptional activity (By similarity).
Gene: CAMK2A
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分子量
- 50kDa
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基因ID
- 815
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UniProt
- Q9UQM7, Q13557
抗原
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