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CABP1 抗体 (Internal Region)

This anti-CABP1 antibody is a 兔 多克隆 antibody detecting CABP1 in WB 和 ELISA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6260388
发货至: 中国

Quick Overview for CABP1 抗体 (Internal Region) (ABIN6260388)

抗原

See all CABP1 抗体
CABP1 (Calcium Binding Protein 1 (CABP1))

适用

人, 小鼠, 大鼠

宿主

  • 11
  • 1

克隆类型

  • 11
  • 1
多克隆

标记

  • 12
This CABP1 antibody is un-conjugated

应用范围

  • 11
  • 4
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • 抗原表位

    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region

    特异性

    CABP1 Antibody detects endogenous levels of total CABP1.

    预测反应

    Pig,Bovine,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human CABP1, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    CABP1 (Calcium Binding Protein 1 (CABP1))

    别名

    CABP1

    背景

    Description: Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs)(PubMed:14570872). Inhibits agonist-induced intracellular calcium signaling (PubMed:15980432). Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels (PubMed:11865310). Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but has an opposite effect on channel function (PubMed:15140941). Suppresses the calcium-dependent inactivation of CACNA1D (By similarity). Inhibits TRPC5 channels (PubMed:15895247). Prevents NMDA receptor-induced cellular degeneration. Required for the normal transfer of light signals through the retina (By similarity).

    Gene: CABP1

    分子量

    40 kDa

    基因ID

    9478

    UniProt

    Q9NZU7

    途径

    Synaptic Membrane, Negative Regulation of Transporter Activity
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