BRD7 抗体 (Internal Region)
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北京 101111
Quick Overview for BRD7 抗体 (Internal Region) (ABIN6260310)
抗原
See all BRD7 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- BRD7 Antibody detects endogenous levels of total BRD7.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human BRD7, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Bromodomain Containing 7 (BRD7) (AA 1-95) antibody
BRD7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (C-Term) antibodyBRD7 适用: 人, 大鼠, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 601-651) antibodyBRD7 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 387-418) antibodyBRD7 适用: 小鼠 WB 宿主: 兔 Polyclonal RB43270 unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 514-567) antibodyBRD7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (AA 1-651) antibodyBRD7 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Bromodomain Containing 7 (BRD7) (C-Term) antibodyBRD7 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- BRD7 (Bromodomain Containing 7 (BRD7))
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别名
- BRD7
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背景
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Description: Acts both as coactivator and as corepressor. May play a role in chromatin remodeling. Activator of the Wnt signaling pathway in a DVL1-dependent manner by negatively regulating the GSK3B phosphotransferase activity. Induces dephosphorylation of GSK3B at 'Tyr-216'. Down-regulates TRIM24-mediated activation of transcriptional activation by AR (By similarity). Transcriptional corepressor that down-regulates the expression of target genes. Binds to target promoters, leading to increased histone H3 acetylation at 'Lys-9' (H3K9ac). Binds to the ESR1 promoter. Recruits BRCA1 and POU2F1 to the ESR1 promoter. Coactivator for TP53-mediated activation of transcription of a set of target genes. Required for TP53-mediated cell-cycle arrest in response to oncogene activation. Promotes acetylation of TP53 at 'Lys-382', and thereby promotes efficient recruitment of TP53 to target promoters. Inhibits cell cycle progression from G1 to S phase.
Gene: BRD7
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分子量
- 70-74 kDa
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基因ID
- 29117
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UniProt
- Q9NPI1
抗原
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