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Aurora Kinase C 抗体 (N-Term)

AURKC 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6260157
发货至: 中国
  • 抗原 See all Aurora Kinase C (AURKC) 抗体
    Aurora Kinase C (AURKC)
    抗原表位
    • 9
    • 9
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    • 5
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    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    N-Term
    适用
    • 58
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    • 17
    • 1
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    • 1
    • 1
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    宿主
    • 57
    • 2
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    克隆类型
    • 60
    多克隆
    标记
    • 32
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    This Aurora Kinase C antibody is un-conjugated
    应用范围
    • 53
    • 30
    • 20
    • 13
    • 9
    • 3
    • 1
    Western Blotting (WB), ELISA
    特异性
    AurB/C Antibody detects endogenous levels of total AurB/C.
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human AurB/C, corresponding to a region within N-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product AURKC Primary Antibody
  • 应用备注
    WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    Aurora Kinase C (AURKC)
    别名
    AURKC (AURKC 产品)
    别名
    AURKC antibody, AIE2 antibody, AIK3 antibody, ARK3 antibody, AurC antibody, SPGF5 antibody, STK13 antibody, aurora-C antibody, AIE1 antibody, ARK-3 antibody, IAK3 antibody, Stk13 antibody, aurora kinase C antibody, AURKC antibody, Aurkc antibody
    背景

    Description: Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at 'Ser-10' and 'Ser-28'. AURKC phosphorylates the CPC complex subunits BIRC5/survivin and INCENP leading to increased AURKC activity. Phosphorylates TACC1, another protein involved in cell division, at 'Ser-228'.

    Gene: AURKC

    分子量
    36 kDa
    基因ID
    6795
    UniProt
    Q9UQB9
    途径
    Cell Division Cycle, Maintenance of Protein Location
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