Aurora Kinase C 抗体 (N-Term)
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北京 101111
Quick Overview for Aurora Kinase C 抗体 (N-Term) (ABIN6260157)
抗原
See all Aurora Kinase C (AURKC) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- AurB/C Antibody detects endogenous levels of total AurB/C.
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human AurB/C, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Aurora Kinase C (AURKC) (AA 12-143) antibody
AURKC 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aurora Kinase C (AURKC) (AA 3-38) antibodyAURKC 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Aurora Kinase C (AURKC) (AA 3-38), (N-Term) antibodyAURKC 适用: 人 WB 宿主: 兔 Polyclonal RB6507 unconjugated
anti-Aurora Kinase C (AURKC) antibodyAURKC 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aurora Kinase C (AURKC) (C-Term) antibodyAURKC 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB0881 unconjugated
anti-Aurora Kinase C (AURKC) (AA 5-237) antibodyAURKC 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aurora Kinase C (AURKC) (AA 115-145) antibodyAURKC 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB6822 unconjugated
anti-Aurora Kinase C (AURKC) (AA 115-145) antibodyAURKC 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Aurora Kinase C (AURKC) (AA 1-30) antibodyAURKC 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Aurora Kinase C (AURKC) (C-Term) antibodyAURKC 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- Aurora Kinase C (AURKC)
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别名
- AURKC
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背景
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Description: Serine/threonine-protein kinase component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Plays also a role in meiosis and more particularly in spermatogenesis. Has redundant cellular functions with AURKB and can rescue an AURKB knockdown. Like AURKB, AURKC phosphorylates histone H3 at 'Ser-10' and 'Ser-28'. AURKC phosphorylates the CPC complex subunits BIRC5/survivin and INCENP leading to increased AURKC activity. Phosphorylates TACC1, another protein involved in cell division, at 'Ser-228'.
Gene: AURKC
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分子量
- 36 kDa
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基因ID
- 6795
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UniProt
- Q9UQB9
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途径
- Cell Division Cycle, Maintenance of Protein Location
抗原
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