ATXN7L3 抗体 (Internal Region)
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北京 101111
Quick Overview for ATXN7L3 抗体 (Internal Region) (ABIN6260152)
抗原
See all ATXN7L3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- ATXN7L3 Antibody detects endogenous levels of total ATXN7L3.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human ATXN7L3, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Ataxin 7-Like 3 (ATXN7L3) antibody
ATXN7L3 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 7-Like 3 (ATXN7L3) (AA 51-347) antibodyATXN7L3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 7-Like 3 (ATXN7L3) (AA 126-175) antibodyATXN7L3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Pig, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- ATXN7L3 (Ataxin 7-Like 3 (ATXN7L3))
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别名
- ATXN7L3
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背景
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Description: Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B (PubMed:18206972, PubMed:21746879). The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex (PubMed:18206972). Regulates H2B monoubiquitination (H2Bub1) levels. Affects subcellular distribution of ENY2, USP22 and ATXN7L3B (PubMed:27601583).
Gene: ATXN7L3
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分子量
- 39 kDa
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基因ID
- 56970
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UniProt
- Q14CW9
抗原
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