ASPM 抗体 (Internal Region)
Quick Overview for ASPM 抗体 (Internal Region) (ABIN6260082)
抗原
See all ASPM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- ASPM Antibody detects endogenous levels of total ASPM.
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预测反应
- Bovine,Horse,Sheep,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human ASPM, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Asp (Abnormal Spindle) Homolog, Microcephaly Associated (ASPM) (AA 101-234) antibody
ASPM 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Asp (Abnormal Spindle) Homolog, Microcephaly Associated (ASPM) antibodyASPM 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- ASPM (Asp (Abnormal Spindle) Homolog, Microcephaly Associated (ASPM))
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别名
- ASPM
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背景
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Description: Involved in mitotic spindle regulation and coordination of mitotic processes. The function in regulating microtubule dynamics at spindle poles including spindle orientation, astral microtubule density and poleward microtubule flux seems to depend on the association with the katanin complex formed by KATNA1 and KATNB1. Enhances the microtubule lattice severing activity of KATNA1 by recruiting the katanin complex to microtubules. Can block microtubule minus-end growth and reversely this function can be enhanced by the katanin complex (PubMed:28436967). May have a preferential role in regulating neurogenesis.
Gene: ASPM
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分子量
- 410 kDa
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基因ID
- 259266
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UniProt
- Q8IZT6
抗原
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