ARRDC1 抗体 (C-Term)
-
- 抗原 See all ARRDC1 products
- ARRDC1 (Arrestin Domain Containing 1 (ARRDC1))
-
抗原表位
- C-Term
-
适用
- 人, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ARRDC1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
- 特异性
- Arrdc1 Antibody detects endogenous levels of total Arrdc1.
- 预测反应
- Pig,Bovine,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human Arrdc1, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
-
anti-Arrestin Domain Containing 1 (ARRDC1) (AA 288-433) antibody
ARRDC1 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Arrestin Domain Containing 1 (ARRDC1) (Internal Region) antibodyARRDC1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arrestin Domain Containing 1 (ARRDC1) (Internal Region) antibodyARRDC1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arrestin Domain Containing 1 (ARRDC1) (AA 167-216) antibodyARRDC1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arrestin Domain Containing 1 (ARRDC1) (Center) antibodyARRDC1 适用: 人 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- WB 1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
-
- 抗原
- ARRDC1 (Arrestin Domain Containing 1 (ARRDC1))
- 别名
- ARRDC1 (ARRDC1 产品)
- 别名
- AI957342 antibody, BC004091 antibody, arrestin domain containing 1 antibody, ARRDC1 antibody, Arrdc1 antibody
- 背景
-
Description: Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (PubMed:23886940, PubMed:27462458). Through an ubiquitination-dependent mechanism plays for instance a role in the incorporation of SLC11A2 into extracellular vesicles (PubMed:27462458). More generally, plays a role in the extracellular transport of proteins between cells through the release in the extracellular space of microvesicles (PubMed:22315426). By participating to the ITCH-mediated ubiquitination and subsequent degradation of NOTCH1, negatively regulates the NOTCH signaling pathway (PubMed:23886940).
Gene: ARRDC1
- 分子量
- 48kDa
- 基因ID
- 92714
- UniProt
- Q8N5I2
-
