ARRDC1 抗体 (C-Term)
Quick Overview for ARRDC1 抗体 (C-Term) (ABIN6260054)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Arrdc1 Antibody detects endogenous levels of total Arrdc1.
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预测反应
- Pig,Bovine,Rabbit,Dog,Chicken,Xenopus
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human Arrdc1, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Arrestin Domain Containing 1 (ARRDC1) (AA 288-433) antibody
ARRDC1 适用: 人 ELISA, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Arrestin Domain Containing 1 (ARRDC1) (Internal Region) antibodyARRDC1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arrestin Domain Containing 1 (ARRDC1) (Internal Region) antibodyARRDC1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arrestin Domain Containing 1 (ARRDC1) (AA 167-216) antibodyARRDC1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Arrestin Domain Containing 1 (ARRDC1) (Center) antibodyARRDC1 适用: 人 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-Arrestin Domain Containing 1 (ARRDC1) (Internal Region) antibodyARRDC1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- ARRDC1 (Arrestin Domain Containing 1 (ARRDC1))
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别名
- ARRDC1
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背景
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Description: Functions as an adapter recruiting ubiquitin-protein ligases to their specific substrates (PubMed:23886940, PubMed:27462458). Through an ubiquitination-dependent mechanism plays for instance a role in the incorporation of SLC11A2 into extracellular vesicles (PubMed:27462458). More generally, plays a role in the extracellular transport of proteins between cells through the release in the extracellular space of microvesicles (PubMed:22315426). By participating to the ITCH-mediated ubiquitination and subsequent degradation of NOTCH1, negatively regulates the NOTCH signaling pathway (PubMed:23886940).
Gene: ARRDC1
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分子量
- 48kDa
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基因ID
- 92714
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UniProt
- Q8N5I2
抗原
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