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ARL3 抗体 (C-Term)

This anti-ARL3 antibody is a 兔 多克隆 antibody detecting ARL3 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6260040
发货至: 中国

Quick Overview for ARL3 抗体 (C-Term) (ABIN6260040)

抗原

See all ARL3 抗体
ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))

适用

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人, 小鼠, 大鼠

宿主

  • 47
  • 6

克隆类型

  • 49
  • 4
多克隆

标记

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This ARL3 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    特异性

    ARL3 Antibody detects endogenous levels of total ARL3.

    预测反应

    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human ARL3, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    ARL3 (ADP-Ribosylation Factor-Like 3 (ARL3))

    别名

    ARL3

    背景

    Description: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Requires assistance from GTPase-activating proteins (GAPs) like RP2 and PDE6D, in order to cycle between inactive GDP-bound and active GTP-bound forms. Required for targeting proteins such as NPHP3 to the ciliary membrane by releasing myristoylated NPHP3 from UNC119B cargo adapter into the cilium. Does not act as an allosteric activator of the cholera toxin catalytic subunit.

    Gene: ARL3

    分子量

    20 kDa

    基因ID

    403

    UniProt

    P36405
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