ARHGEF4 抗体 (Internal Region)
Quick Overview for ARHGEF4 抗体 (Internal Region) (ABIN6260035)
抗原
See all ARHGEF4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- ARHGEF4 Antibody detects endogenous levels of total ARHGEF4.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human ARHGEF4, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) (N-Term) antibody
ARHGEF4 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) (N-Term) antibodyVerified ARHGEF4 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) (AA 143-271) antibodyARHGEF4 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal ARHGEF-08 unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) (AA 143-271) antibody (PE)ARHGEF4 适用: 人 ICFC 宿主: 小鼠 Monoclonal ARHGEF-08 PE
anti-rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) (AA 1-100) antibodyARHGEF4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4) (AA 51-100) antibodyARHGEF4 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:1000-3000, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- ARHGEF4 (rho Guanine Nucleotide Exchange Factor (GEF) 4 (ARHGEF4))
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别名
- ARHGEF4
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背景
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Description: Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.
Gene: ARHGEF4
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分子量
- 79 kDa
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基因ID
- 50649
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UniProt
- Q9NR80
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途径
- Neurotrophin Signaling Pathway
抗原
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