ARHGDIA 抗体 (N-Term)
Quick Overview for ARHGDIA 抗体 (N-Term) (ABIN6260030)
抗原
See all ARHGDIA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- ARHGDIA Antibody detects endogenous levels of total ARHGDIA.
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预测反应
- Pig,Bovine,Horse,Sheep,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human ARHGDIA, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA) (AA 1-204) antibody
ARHGDIA 适用: 人, 小鼠, 猴 WB, ELISA, FACS, ICC 宿主: 小鼠 Monoclonal 2G3 unconjugated
anti-rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA) (AA 1-204) antibodyARHGDIA 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA) (AA 1-204) antibodyARHGDIA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA) (AA 1-204) antibodyARHGDIA 适用: 人, 小鼠, 猴 WB, ELISA, FACS, IF/ICC 宿主: 小鼠 Monoclonal unconjugated
anti-rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA) antibodyARHGDIA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA) antibodyARHGDIA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA) (AA 112-140), (C-Term) antibodyARHGDIA 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20512 unconjugated
anti-rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA) (AA 2-204) antibodyARHGDIA 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA) (AA 1-204) antibodyARHGDIA 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA) antibodyKO Validated ARHGDIA 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- ARHGDIA (rho GDP Dissociation Inhibitor (GDI) alpha (ARHGDIA))
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别名
- ARHGDIA
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背景
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Description: Controls Rho proteins homeostasis. Regulates the GDP/GTP exchange reaction of the Rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them. Retains Rho proteins such as CDC42, RAC1 and RHOA in an inactive cytosolic pool, regulating their stability and protecting them from degradation. Actively involved in the recycling and distribution of activated Rho GTPases in the cell, mediates extraction from membranes of both inactive and activated molecules due its exceptionally high affinity for prenylated forms. Through the modulation of Rho proteins, may play a role in cell motility regulation. In glioma cells, inhibits cell migration and invasion by mediating the signals of SEMA5A and PLXNB3 that lead to inactivation of RAC1.
Gene: ARHGDIA
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分子量
- 28kDa
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基因ID
- 396
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UniProt
- P52565
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途径
- Neurotrophin Signaling Pathway
抗原
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