Annexin a1 抗体 (N-Term)
Quick Overview for Annexin a1 抗体 (N-Term) (ABIN6259948)
抗原
See all Annexin a1 (ANXA1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- Annexin A1 Antibody detects endogenous levels of total Annexin A1.
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human Annexin A1, corresponding to a region within N-terminal amino acids.
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亚型
- IgG
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anti-Annexin A1 (ANXA1) (AA 6-346) antibody
ANXA1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) (AA 1-346) antibodyANXA1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) antibodyANXA1 适用: 人 IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal ANXA1-3566 unconjugated
anti-Annexin A1 (ANXA1) (AA 144-248) antibodyANXA1 适用: 人, 小鼠, 猴 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 2F1 unconjugated
anti-Annexin A1 (ANXA1) antibodyANXA1 适用: 人 WB, IP, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) (C-Term) antibodyVerified ANXA1 适用: 人, 小鼠, 大鼠, Pig WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) (AA 1-346) antibodyANXA1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D11 unconjugated
anti-Annexin A1 (ANXA1) (AA 1-346) antibodyANXA1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Annexin A1 (ANXA1) antibodyANXA1 适用: 人 IHC, FACS, StM 宿主: 小鼠 Monoclonal ANXA1-1671 unconjugated
anti-Annexin A1 (ANXA1) antibodyANXA1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- Annexin a1 (ANXA1) (Annexin A1 (ANXA1))
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别名
- ANXA1
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背景
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Description: Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity (PubMed:8425544). Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response (By similarity). Promotes resolution of inflammation and wound healing (PubMed:25664854). Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades (PubMed:15187149, PubMed:25664854). Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (PubMed:15187149). Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T-cells (PubMed:17008549). Promotes the differentiation of T-cells into Th1 cells and negatively regulates differentiation into Th2 cells (PubMed:17008549). Has no effect on unstimulated T cells (PubMed:17008549). Promotes rearrangement of the actin cytoskeleton, cell polarization and cell migration (PubMed:15187149). Negatively regulates hormone exocytosis via activation of the formyl peptide receptors and reorganization of the actin cytoskeleton (PubMed:19625660). Has high affinity for Ca2+ and can bind up to eight Ca2+ ions (By similarity). Displays Ca2+-dependent binding to phospholipid membranes (PubMed:2532504, PubMed:8557678). Plays a role in the formation of phagocytic cups and phagosomes. Plays a role in phagocytosis by mediating the Ca2+-dependent interaction between phagosomes and the actin cytoskeleton (By similarity).
Gene: ANXA1
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分子量
- 39kDa
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基因ID
- 301
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UniProt
- P04083
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途径
- Hormone Transport
抗原
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