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AFG3L2 抗体 (C-Term)

This anti-AFG3L2 antibody is a 兔 多克隆 antibody detecting AFG3L2 in WB 和 IHC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6259816
发货至: 中国
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Quick Overview for AFG3L2 抗体 (C-Term) (ABIN6259816)

抗原

See all AFG3L2 抗体
AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

适用

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人, 小鼠, 大鼠

宿主

  • 40
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克隆类型

  • 42
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多克隆

标记

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This AFG3L2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    特异性

    AFG3L2 Antibody detects endogenous levels of total AFG3L2.

    预测反应

    Pig,Bovine,Sheep,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human AFG3L2, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    AFG3L2 (AFG3-Like Protein 2 (AFG3L2))

    别名

    AFG3L2

    背景

    Description: ATP-dependent protease which is essential for axonal and neuron development. In neurons, mediates degradation of SMDT1/EMRE before its assembly with the uniporter complex, limiting the availability of SMDT1/EMRE for MCU assembly and promoting efficient assembly of gatekeeper subunits with MCU (PubMed:27642048). Required for the maturation of paraplegin (SPG7) after its cleavage by mitochondrial-processing peptidase (MPP), converting it into a proteolytically active mature form (By similarity).

    Gene: AFG3L2

    分子量

    80-90 kDa

    基因ID

    10939

    UniProt

    Q9Y4W6

    途径

    Skeletal Muscle Fiber Development
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