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AFF4 抗体 (C-Term)

This anti-AFF4 antibody is a 兔 多克隆 antibody detecting AFF4 in WB, ELISA 和 IHC. Suitable for 人 和 小鼠.
产品编号 ABIN6259815
发货至: 中国

Quick Overview for AFF4 抗体 (C-Term) (ABIN6259815)

抗原

See all AFF4 抗体
AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

适用

  • 53
  • 7
  • 5
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  • 1
人, 小鼠

宿主

  • 47
  • 6

克隆类型

  • 50
  • 3
多克隆

标记

  • 30
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This AFF4 antibody is un-conjugated

应用范围

  • 30
  • 23
  • 13
  • 13
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
  • 抗原表位

    • 15
    • 10
    • 7
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    AFF4 Antibody detects endogenous levels of total AFF4.

    预测反应

    Pig,Bovine,Horse,Sheep,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human AFF4, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:1000-3000, IHC 1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    AFF4 (AF4/FMR2 Family, Member 4 (AFF4))

    别名

    AFF4

    背景

    Description: Key component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other factors through direct interactions with ELL proteins (ELL, ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus, the SEC complex is recruited by the viral Tat protein to stimulate viral gene expression.

    Gene: AFF4

    分子量

    127kDa

    基因ID

    27125

    UniProt

    Q9UHB7
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