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ADRM1 抗体 (Internal Region)

This anti-ADRM1 antibody is a 兔 多克隆 antibody detecting ADRM1 in WB, IHC, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6259812
发货至: 中国

Quick Overview for ADRM1 抗体 (Internal Region) (ABIN6259812)

抗原

See all ADRM1 (Adrm1) 抗体
ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This ADRM1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    Internal Region

    特异性

    ADRM1 Antibody detects endogenous levels of total ADRM1.

    预测反应

    Zebrafish,Bovine,Horse,Sheep,Dog,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human ADRM1, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

    别名

    ADRM1

    背景

    Description: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. Within the complex, functions as a proteasomal ubiquitin receptor. Engages and activates 19S-associated deubiquitinases UCHL5 and PSMD14 during protein degradation. UCHL5 reversibly associate with the 19S regulatory particle whereas PSMD14 is an intrinsic subunit of the proteasome lid subcomplex.

    Gene: ADRM1

    分子量

    46 kDa

    基因ID

    11047

    UniProt

    Q16186

    途径

    Positive Regulation of Endopeptidase Activity
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