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TADA2L 抗体

This anti-TADA2L antibody is a 兔 多克隆 antibody detecting TADA2L in WB, ELISA, IF 和 ICC. Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN6259764
发货至: 中国

Quick Overview for TADA2L 抗体 (ABIN6259764)

抗原

See all TADA2L (TADA2A) 抗体
TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))

适用

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人, 小鼠, 大鼠, 猴

宿主

  • 38
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克隆类型

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多克隆

标记

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This TADA2L antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 特异性

    ADA2L antibody detects endogenous levels of total ADA2L

    交叉反应

    人, 猴, 小鼠, 大鼠

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human ADA2L

    亚型

    IgG
  • 应用备注

    WB: 1:500~1:3000, IF/ICC 1:100-1:500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C.Stable for 12 months from date of receipt

    有效期

    12 months
  • 抗原

    TADA2L (TADA2A) (Transcriptional Adaptor 2A (TADA2A))

    别名

    ADA2L

    背景

    Description: Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4. Required for the function of some acidic activation domains, which activate transcription from a distant site (By similarity). Binds double-stranded DNA. Binds dinucleosomes, probably at the linker region between neighboring nucleosomes. Plays a role in chromatin remodeling. May promote TP53/p53 'Lys-321' acetylation, leading to reduced TP53 stability and transcriptional activity (PubMed:22644376). May also promote XRCC6 acetylation thus facilitating cell apoptosis in response to DNA damage (PubMed:22644376).

    Gene: TADA2A

    分子量

    47kDa

    基因ID

    6871

    UniProt

    O75478

    途径

    Chromatin Binding
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