LYAR 抗体 (Internal Region)
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北京 101111
Quick Overview for LYAR 抗体 (Internal Region) (ABIN6259573)
抗原
See all LYAR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- LYAR Antibody detects endogenous levels of total LYAR.
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预测反应
- Sheep
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human LYAR, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Ly1 Antibody Reactive (LYAR) (AA 270-388) antibody
LYAR 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ly1 Antibody Reactive (LYAR) (AA 10-160) antibodyLYAR 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ly1 Antibody Reactive (LYAR) (AA 1-379) antibodyLYAR 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Ly1 Antibody Reactive (LYAR) (AA 1-379) antibodyLYAR 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Ly1 Antibody Reactive (LYAR) (AA 288-379) antibodyLYAR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ly1 Antibody Reactive (LYAR) (AA 271-386) antibodyLYAR 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ly1 Antibody Reactive (LYAR) antibodyLYAR 适用: 人 WB 宿主: 小鼠 Monoclonal 25GB8235 unconjugated
anti-Ly1 Antibody Reactive (LYAR) antibodyLYAR 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ly1 Antibody Reactive (LYAR) (AA 179-228) antibodyLYAR WB 宿主: 兔 Polyclonal unconjugated
anti-Ly1 Antibody Reactive (LYAR) (AA 81-130) antibodyLYAR 适用: 人, 小鼠, 大鼠, 马, 豚鼠, 兔, 斑马鱼, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- LYAR (Ly1 Antibody Reactive (LYAR))
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别名
- LYAR
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物质类
- Antibody
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背景
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Description: Plays a role in the maintenance of the appropriate processing of 47S/45S pre-rRNA to 32S/30S pre-rRNAs and their subsequent processing to produce 18S and 28S rRNAs (PubMed:24495227). Also acts at the level of transcription regulation. Along with PRMT5, binds the gamma-globin (HBG1/HBG2) promoter and represses its expression (PubMed:25092918). In neuroblastoma cells, may also repress the expression of oxidative stress genes, including CHAC1, HMOX1, SLC7A11, ULBP1 and SNORD41 that encodes a small nucleolar RNA (PubMed:28686580). Preferentially binds to a DNA motif containing 5'-GGTTAT-3' (PubMed:25092918). Stimulates phagocytosis of photoreceptor outer segments by retinal pigment epithelial cells (By similarity). Prevents nucleolin/NCL self-cleavage, maintaining a normal steady-state level of NCL protein in undifferentiated embryonic stem cells (ESCs), which in turn is essential for ESC self-renewal (By similarity).
Gene: LYAR
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分子量
- 44 kDa
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基因ID
- 55646
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UniProt
- Q9NX58
抗原
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