WEE2 抗体
Our Local Distributor
北京 101111
Quick Overview for WEE2 抗体 (ABIN6259536)
抗原
See all WEE2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- WEE2 Antibody detects endogenous levels of total WEE2
-
交叉反应
- 人, 小鼠
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide
-
亚型
- IgG
-
-
anti-WEE1 Homolog 2 (S. Pombe) (WEE2) (AA 364-393) antibody
WEE2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-WEE1 Homolog 2 (S. Pombe) (WEE2) (AA 364-393) antibodyWEE2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500~1:1000, IF/ICC 1:100-1:500
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
-
有效期
- 12 months
-
-
- WEE2 (WEE1 Homolog 2 (S. Pombe) (WEE2))
-
别名
- WEE2
-
背景
-
Description: Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity).
Gene: WEE2
-
分子量
- 60 kDa
-
基因ID
- 494551
-
UniProt
- P0C1S8
-
途径
- M Phase
抗原
-
