WEE2 抗体 (Internal Region)
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北京 101111
Quick Overview for WEE2 抗体 (Internal Region) (ABIN6259536)
抗原
See all WEE2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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原理
- WEE2 Antibody
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特异性
- WEE2 Antibody detects endogenous levels of total WEE2
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预测反应
- Pig,Horse,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human WEE2, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-WEE1 Homolog 2 (S. Pombe) (WEE2) (AA 364-393) antibody
WEE2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-WEE1 Homolog 2 (S. Pombe) (WEE2) (AA 364-393) antibodyWEE2 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- WEE2 (WEE1 Homolog 2 (S. Pombe) (WEE2))
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别名
- WEE2
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背景
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Description: Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle (GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation (By similarity).
Gene: WEE2
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分子量
- 60 kDa
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基因ID
- 494551
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UniProt
- P0C1S8
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途径
- M Phase
抗原
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