RFTN1 抗体 (Internal Region)
Our Local Distributor
北京 101111
Quick Overview for RFTN1 抗体 (Internal Region) (ABIN6259466)
抗原
See all RFTN1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Internal Region
-
特异性
- RFTN1 Antibody detects endogenous levels of total RFTN1.
-
预测反应
- Horse,Dog
-
纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
-
免疫原
- A synthesized peptide derived from human RFTN1, corresponding to a region within the internal amino acids.
-
亚型
- IgG
-
-
anti-Raftlin, Lipid Raft Linker 1 (RFTN1) (AA 288-520) antibody
RFTN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Raftlin, Lipid Raft Linker 1 (RFTN1) (AA 207-451) antibodyRFTN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Raftlin, Lipid Raft Linker 1 (RFTN1) (C-Term) antibodyRFTN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Raftlin, Lipid Raft Linker 1 (RFTN1) (AA 169-198) antibodyRFTN1 适用: 人 WB 宿主: 兔 Polyclonal RB41751 unconjugated
anti-Raftlin, Lipid Raft Linker 1 (RFTN1) (C-Term) antibodyRFTN1 适用: 人, 小鼠, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Raftlin, Lipid Raft Linker 1 (RFTN1) antibodyRFTN1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
-
有效期
- 12 months
-
-
- RFTN1 (Raftlin, Lipid Raft Linker 1 (RFTN1))
-
别名
- RFTN1
-
背景
-
Description: Involved in protein trafficking via association with clathrin and AP2 complex (PubMed:27022195, PubMed:21266579). Upon bacterial lipopolysaccharide stimulation, mediates internalization of TLR4 to endosomes in dendritic cells and macrophages, and internalization of poly(I:C) to TLR3-positive endosomes in myeloid dendritic cells and epithelial cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production (PubMed:27022195, PubMed:21266579). Involved in T-cell antigen receptor-mediated signaling by regulating tyrosine kinase LCK localization, T-cell dependent antibody production and cytokine secretion (By similarity). May regulate B-cell antigen receptor-mediated signaling (PubMed:12805216). May play a pivotal role in the formation and/or maintenance of lipid rafts (PubMed:12805216).
Gene: RFTN1
-
分子量
- 63 kDa
-
基因ID
- 23180
-
UniProt
- Q14699
抗原
-
