RFTN1 抗体 (Internal Region)
Quick Overview for RFTN1 抗体 (Internal Region) (ABIN6259466)
抗原
See all RFTN1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- RFTN1 Antibody detects endogenous levels of total RFTN1.
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预测反应
- Horse,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human RFTN1, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Raftlin, Lipid Raft Linker 1 (RFTN1) (AA 288-520) antibody
RFTN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Raftlin, Lipid Raft Linker 1 (RFTN1) (AA 207-451) antibodyRFTN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Raftlin, Lipid Raft Linker 1 (RFTN1) (C-Term) antibodyRFTN1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Raftlin, Lipid Raft Linker 1 (RFTN1) (AA 169-198) antibodyRFTN1 适用: 人 WB 宿主: 兔 Polyclonal RB41751 unconjugated
anti-Raftlin, Lipid Raft Linker 1 (RFTN1) (C-Term) antibodyRFTN1 适用: 人, 小鼠, 大鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Raftlin, Lipid Raft Linker 1 (RFTN1) antibodyRFTN1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- RFTN1 (Raftlin, Lipid Raft Linker 1 (RFTN1))
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别名
- RFTN1
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背景
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Description: Involved in protein trafficking via association with clathrin and AP2 complex (PubMed:27022195, PubMed:21266579). Upon bacterial lipopolysaccharide stimulation, mediates internalization of TLR4 to endosomes in dendritic cells and macrophages, and internalization of poly(I:C) to TLR3-positive endosomes in myeloid dendritic cells and epithelial cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production (PubMed:27022195, PubMed:21266579). Involved in T-cell antigen receptor-mediated signaling by regulating tyrosine kinase LCK localization, T-cell dependent antibody production and cytokine secretion (By similarity). May regulate B-cell antigen receptor-mediated signaling (PubMed:12805216). May play a pivotal role in the formation and/or maintenance of lipid rafts (PubMed:12805216).
Gene: RFTN1
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分子量
- 63 kDa
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基因ID
- 23180
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UniProt
- Q14699
抗原
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