ALKBH5 抗体 (Internal Region)
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Quick Overview for ALKBH5 抗体 (Internal Region) (ABIN6259460)
抗原
See all ALKBH5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- ALKBH5 Antibody detects endogenous levels of total ALKBH5.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human ALKBH5, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-AlkB, Alkylation Repair Homolog 5 (ALKBH5) (AA 245-394) antibody
ALKBH5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 5 (ALKBH5) (AA 302-330) antibodyALKBH5 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB38474 unconjugated
anti-AlkB, Alkylation Repair Homolog 5 (ALKBH5) (AA 1-458) antibodyALKBH5 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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有效期
- 12 months
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- ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))
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别名
- ALKBH5
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背景
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Description: Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N6-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Can also demethylate N6-methyladenosine in single-stranded DNA (in vitro) (PubMed:24616105). Requires molecular oxygen, alpha-ketoglutarate and iron (PubMed:21264265, PubMed:23177736, PubMed:24778178, PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export (PubMed:23177736). Required for spermatogenesis (By similarity).
Gene: ALKBH5
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分子量
- ?44 kDa
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基因ID
- 54890
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UniProt
- Q6P6C2
抗原
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