STK36 抗体 (Internal Region)
Quick Overview for STK36 抗体 (Internal Region) (ABIN6259306)
抗原
See all STK36 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- STK36 Antibody detects endogenous levels of total STK36.
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预测反应
- Pig,Bovine,Horse,Sheep,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human STK36, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-serine/threonine Kinase 36 (STK36) (AA 1-1315) antibody
STK36 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 36 (STK36) (AA 1-1315) antibodySTK36 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-serine/threonine Kinase 36 (STK36) (AA 250-450) antibodySTK36 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-serine/threonine Kinase 36 (STK36) (AA 387-436) antibodySTK36 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- STK36 (serine/threonine Kinase 36 (STK36))
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别名
- STK36
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背景
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Description: Serine/threonine protein kinase which plays an important role in the sonic hedgehog (Shh) pathway by regulating the activity of GLI transcription factors (PubMed:10806483). Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization (PubMed:10806483). GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur (PubMed:10806483). Required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function (By similarity). Essential for construction of the central pair apparatus of motile cilia.
Gene: STK36
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分子量
- 170 kDa
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基因ID
- 27148
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UniProt
- Q9NRP7
抗原
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