PSPC1 抗体 (C-Term)
Quick Overview for PSPC1 抗体 (C-Term) (ABIN6259284)
抗原
See all PSPC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- PSPC1 Antibody detects endogenous levels of total PSPC1.
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预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Chicken
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human PSPC1, corresponding to a region within C-terminal amino acids.
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亚型
- IgG
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anti-Paraspeckle Component 1 (PSPC1) (AA 1-70) antibody
PSPC1 适用: 人 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Paraspeckle Component 1 (PSPC1) antibodyPSPC1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Paraspeckle Component 1 (PSPC1) antibodyPSPC1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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有效期
- 12 months
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- PSPC1 (Paraspeckle Component 1 (PSPC1))
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别名
- PSPC1
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背景
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Description: Regulates, cooperatively with NONO and SFPQ, androgen receptor-mediated gene transcription activity in Sertoli cell line (By similarity). Binds to poly(A), poly(G) and poly(U) RNA homopolymers. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer (By similarity). Together with NONO, required for the formation of nuclear paraspeckles. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway.
Gene: PSPC1
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分子量
- 58 kDa
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基因ID
- 55269
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UniProt
- Q8WXF1
抗原
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