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PPHLN1 抗体 (N-Term)

This anti-PPHLN1 antibody is a 兔 多克隆 antibody detecting PPHLN1 in WB, IHC, ELISA, IF 和 ICC. Suitable for 人 和 小鼠.
产品编号 ABIN6259270
发货至: 中国
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Quick Overview for PPHLN1 抗体 (N-Term) (ABIN6259270)

抗原

See all PPHLN1 抗体
PPHLN1 (Periphilin 1 (PPHLN1))

适用

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人, 小鼠

宿主

  • 34
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克隆类型

  • 35
  • 2
多克隆

标记

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This PPHLN1 antibody is un-conjugated

应用范围

  • 31
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    N-Term

    特异性

    PPHLN Antibody detects endogenous levels of total PPHLN.

    预测反应

    Pig,Sheep,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human PPHLN, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    PPHLN1 (Periphilin 1 (PPHLN1))

    别名

    PPHLN1

    背景

    Description: Component of the HUSH complex, a multiprotein complex that mediates epigenetic repression. The HUSH complex is recruited to genomic loci rich in H3K9me3 and is probably required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3. In the HUSH complex, contributes to the maintenance of the complex at chromatin (PubMed:26022416). Acts as a transcriptional corepressor and regulates the cell cycle, probably via the HUSH complex (PubMed:15474462, PubMed:17963697). May be involved in epithelial differentiation by contributing to epidermal integrity and barrier formation (Probable).

    Gene: PPHLN1

    分子量

    53 kDa

    基因ID

    51535

    UniProt

    Q8NEY8
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