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SRSF3 抗体 (C-Term)

This anti-SRSF3 antibody is a 兔 多克隆 antibody detecting SRSF3 in WB, ELISA, IF 和 ICC. Suitable for 人 和 小鼠.
产品编号 ABIN6259187
发货至: 中国

Quick Overview for SRSF3 抗体 (C-Term) (ABIN6259187)

抗原

See all SRSF3 抗体
SRSF3 (serine/arginine-Rich Splicing Factor 3 (SRSF3))

适用

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人, 小鼠

宿主

  • 30
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克隆类型

  • 28
  • 7
多克隆

标记

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This SRSF3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    C-Term

    特异性

    SFRS3 Antibody detects endogenous levels of total SFRS3.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human SFRS3, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    SRSF3 (serine/arginine-Rich Splicing Factor 3 (SRSF3))

    别名

    SRSF3

    背景

    Description: Splicing factor that specifically promotes exon-inclusion during alternative splicing (PubMed:26876937). Interaction with YTHDC1, a RNA-binding protein that recognizes and binds N6-methyladenosine (m6A)-containing RNAs, promotes recruitment of SRSF3 to its mRNA-binding elements adjacent to m6A sites, leading to exon-inclusion during alternative splicing (PubMed:26876937). Also functions as export adapter involved in mRNA nuclear export such as of histone H2A (PubMed:11336712, PubMed:18364396). Binds mRNA which is thought to be transferred to the NXF1-NXT1 heterodimer for export (TAP/NXF1 pathway), enhances NXF1-NXT1 RNA-binding activity (PubMed:11336712, PubMed:18364396). RNA-binding is semi-sequence specific (PubMed:17036044).

    Gene: SRSF3

    分子量

    25 kDa

    基因ID

    6428

    UniProt

    P84103
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