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SF3B4 抗体 (N-Term)

This anti-SF3B4 antibody is a 兔 多克隆 antibody detecting SF3B4 in WB, ELISA, IHC, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6259186
发货至: 中国

Quick Overview for SF3B4 抗体 (N-Term) (ABIN6259186)

抗原

See all SF3B4 抗体
SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))

适用

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人, 小鼠, 大鼠

宿主

  • 31
  • 5
  • 1

克隆类型

  • 32
  • 5
多克隆

标记

  • 25
  • 2
  • 1
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This SF3B4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 7
    • 4
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    N-Term

    特异性

    SF3B4 Antibody detects endogenous levels of total SF3B4.

    预测反应

    Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human SF3B4, corresponding to a region within N-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    SF3B4 (Splicing Factor 3b, Subunit 4, 49kDa (SF3B4))

    别名

    SF3B4

    背景

    Description: Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex (PubMed:27720643). SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA (PubMed:12234937). May also be involved in the assembly of the 'E' complex. SF3B4 has been found in complex 'B' and 'C' as well (PubMed:10882114). Belongs also to the minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron (PubMed:15146077).

    Gene: SF3B4

    分子量

    55 kDa

    基因ID

    10262

    UniProt

    Q15427
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