PPP1R16B 抗体 (Internal Region)
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北京 101111
Quick Overview for PPP1R16B 抗体 (Internal Region) (ABIN6259165)
抗原
See all PPP1R16B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- PPP1R16B Antibody detects endogenous levels of total PPP1R16B.
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预测反应
- Pig,Zebrafish,Bovine,Horse,Sheep,Rabbit,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human PPP1R16B, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Protein Phosphatase 1, Regulatory Subunit 16B (PPP1R16B) (AA 101-400) antibody
PPP1R16B 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 16B (PPP1R16B) antibodyPPP1R16B 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 16B (PPP1R16B) (AA 1-567) antibodyPPP1R16B 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 16B (PPP1R16B) (AA 1-567) antibodyPPP1R16B 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 16B (PPP1R16B) (AA 57-106) antibodyPPP1R16B 适用: 人, 小鼠, Cow, 犬, 豚鼠, 兔, 大鼠, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Phosphatase 1, Regulatory Subunit 16B (PPP1R16B) (AA 372-399) antibodyPPP1R16B 适用: 人 WB 宿主: 兔 Polyclonal RB37604 unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- PPP1R16B (Protein Phosphatase 1, Regulatory Subunit 16B (PPP1R16B))
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别名
- PPP1R16B
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背景
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Description: Regulator of protein phosphatase 1 (PP1) that acts as a positive regulator of pulmonary endothelial cell (EC) barrier function (PubMed:18586956). Involved in the regulation of the PI3K/AKT signaling pathway, angiogenesis and endothelial cell proliferation (PubMed:25007873). Regulates angiogenesis and endothelial cell proliferation through the control of ECE1 dephosphorylation, trafficking and activity (By similarity). Protects the endothelial barrier from lipopolysaccharide (LPS)-induced vascular leakage (By similarity). Involved in the regulation of endothelial cell filopodia extension (By similarity). May be a downstream target for TGF-beta1 signaling cascade in endothelial cells (PubMed:16263087, PubMed:18586956). Involved in PKA-mediated moesin dephosphorylation which is important in EC barrier protection against thrombin stimulation (PubMed:18586956). Promotes the interaction of PPP1CA with RPSA/LAMR1 and in turn facilitates the dephosphorylation of RPSA/LAMR1 (PubMed:16263087). Involved in the dephosphorylation of EEF1A1 (PubMed:26497934).
Gene: PPP1R16B
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分子量
- 64 kDa
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基因ID
- 26051
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UniProt
- Q96T49
抗原
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