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PARD3 抗体 (C-Term)

The 兔 多克隆 anti-PARD3 antibody (ABIN6259144) specifically detects PARD3 in WB, ELISA, IHC, IF 和 ICC. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6259144
发货至: 中国
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Quick Overview for PARD3 抗体 (C-Term) (ABIN6259144)

抗原

See all PARD3 抗体
PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

适用

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人, 小鼠, 大鼠

宿主

  • 54
  • 3

克隆类型

  • 56
  • 1
多克隆

标记

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This PARD3 antibody is un-conjugated

应用范围

  • 44
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  • 9
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  • 3
  • 3
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Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 15
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    • 2
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    C-Term

    特异性

    PARD3 Antibody detects endogenous levels of total PARD3.

    预测反应

    Bovine,Horse,Sheep,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human PARD3, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    PARD3 (Par-3 Partitioning Defective 3 Homolog (PARD3))

    别名

    PARD3

    背景

    Description: Adapter protein involved in asymmetrical cell division and cell polarization processes (PubMed:27925688, PubMed:10954424). Seems to play a central role in the formation of epithelial tight junctions (PubMed:27925688). Targets the phosphatase PTEN to cell junctions (By similarity). Involved in Schwann cell peripheral myelination (By similarity). Association with PARD6B may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly (By similarity). The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins (PubMed:10934474). Required for establishment of neuronal polarity and normal axon formation in cultured hippocampal neurons (PubMed:19812038, PubMed:27925688).

    Gene: PARD3

    分子量

    151 kDa

    基因ID

    56288

    UniProt

    Q8TEW0

    途径

    Cell-Cell Junction Organization
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