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MRGPRX1 抗体 (C-Term)

This anti-MRGPRX1 antibody is a 兔 多克隆 antibody detecting MRGPRX1 in WB, ELISA, IF 和 ICC. Suitable for 人.
产品编号 ABIN6259084
发货至: 中国

Quick Overview for MRGPRX1 抗体 (C-Term) (ABIN6259084)

抗原

See all MRGPRX1 抗体
MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))

适用

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宿主

  • 24

克隆类型

  • 24
多克隆

标记

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This MRGPRX1 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

    • 6
    • 2
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    C-Term

    特异性

    MRGX1 Antibody detects endogenous levels of total MRGX1.

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human MRGX1, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    MRGPRX1 (MAS-Related GPR, Member X1 (MRGPRX1))

    别名

    MRGPRX1

    背景

    Description: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22)(PubMed:26582731). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner.

    Gene: MRGPRX1

    分子量

    36 kDa

    基因ID

    259249

    UniProt

    Q96LB2
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