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IKZF4 抗体 (C-Term)

This anti-IKZF4 antibody is a 兔 多克隆 antibody detecting IKZF4 in WB, ELISA, IF 和 ICC. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6259025
发货至: 中国

Quick Overview for IKZF4 抗体 (C-Term) (ABIN6259025)

抗原

See all IKZF4 抗体
IKZF4 (IKAROS Family Zinc Finger 4 (Eos) (IKZF4))

适用

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人, 小鼠, 大鼠

宿主

  • 20
  • 5
  • 1

克隆类型

  • 24
  • 2
多克隆

标记

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This IKZF4 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
  • 抗原表位

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    C-Term

    特异性

    IKZF4 Antibody detects endogenous levels of total IKZF4.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human IKZF4, corresponding to a region within C-terminal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    IKZF4 (IKAROS Family Zinc Finger 4 (Eos) (IKZF4))

    别名

    IKZF4

    背景

    Description: DNA-binding protein that binds to the 5'GGGAATRCC-3' Ikaros-binding sequence. Transcriptional repressor. Interacts with SPI1 and MITF to repress transcription of the CTSK and ACP5 promoters via recruitment of corepressors SIN3A and CTBP2. May be involved in the development of central and peripheral nervous systems. Essential for the inhibitory function of regulatory T-cells (Treg). Mediates FOXP3-mediated gene silencing in regulatory T-cells (Treg) via recruitment of corepressor CTBP1 (By similarity).

    Gene: IKZF4

    分子量

    64 kDa

    基因ID

    64375

    UniProt

    Q9H2S9
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