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- 抗原 See all LGR4 抗体
- LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))
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抗原表位
- C-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LGR4 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC)
- 特异性
- GPR48 Antibody detects endogenous levels of total GPR48.
- 预测反应
- Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
- 纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 免疫原
- A synthesized peptide derived from human GPR48, corresponding to a region within C-terminal amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product LGR4 Primary Antibody
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anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) antibody
LGR4 适用: 人 FACS, cELISA 宿主: 大鼠 Monoclonal BBX-1H1 unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) (AA 234-365) antibodyLGR4 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) (Cytoplasmic Domain) antibodyLGR4 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) (C-Term) antibodyLGR4 适用: 人, 猴, 兔, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) (AA 852-950) antibodyLGR4 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 8F6 unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) (AA 320-540) antibodyLGR4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) (Internal Region) antibodyLGR4 适用: 人, Chimpanzee, Macaque ELISA, WB, IHC 宿主: 小鼠 Monoclonal 6G8-B3-G5-C3 unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) (N-Term) antibodyLGR4 适用: 人, 小鼠, 大鼠, 猴, 兔, Pig IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) (2nd Cytoplasmic Domain) antibodyLGR4 适用: 人, Orang-Utan, Gorilla IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4) (Extracellular Domain) antibodyLGR4 适用: 人, 小鼠, 大鼠, 猴, 兔, Pig IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB 1:500-1:1000, IHC 1:50-1:200, ELISA(peptide) 1:20000-1:40000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
- 有效期
- 12 months
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- 抗原
- LGR4 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 4 (LGR4))
- 别名
- LGR4 (LGR4 产品)
- 别名
- BNMD17 antibody, GPR48 antibody, 9130225G07 antibody, A330106J01Rik antibody, A930009A08Rik antibody, Gpr48 antibody, leucine rich repeat containing G protein-coupled receptor 4 antibody, leucine-rich repeat-containing G protein-coupled receptor 4 antibody, LGR4 antibody, Lgr4 antibody
- 背景
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Description: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and is involved in the formation of various organs. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Its function as activator of the Wnt signaling pathway is required for the development of various organs, including liver, kidney, intestine, bone, reproductive tract and eye. May also act as a receptor for norrin (NDP), such results however require additional confirmation in vivo. Required during spermatogenesis to activate the Wnt signaling pathway in peritubular myoid cells. Required for the maintenance of intestinal stem cells and Paneth cell differentiation in postnatal intestinal crypts. Acts as a regulator of bone formation and remodeling. Involved in kidney development, required for maintaining the ureteric bud in an undifferentiated state. Involved in the development of the anterior segment of the eye. Required during erythropoiesis. Also acts as a negative regulator of innate immunity by inhibiting TLR2/TLR4 associated pattern-recognition and proinflammatory cytokine production. Plays an important role in regulating the circadian rhythms of plasma lipids, partially through regulating the rhythmic expression of MTTP (By similarity).
Gene: LGR4
- 分子量
- 100 kDa
- 基因ID
- 55366
- UniProt
- Q9BXB1
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