GNL3L 抗体
Quick Overview for GNL3L 抗体 (ABIN6258968)
抗原
See all GNL3L 抗体适用
宿主
克隆类型
标记
应用范围
- 
    - 
                                            特异性
- GNL3L Antibody detects endogenous levels of total GNL3L
- 
                                            交叉反应
- 人
- 
                                            纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
- 
                                            免疫原
- A synthesized peptide
- 
                                            亚型
- IgG
 
- 
                                            
- 
    
- 
    - 
                                            应用备注
- WB 1:500~1:1000, IF/ICC 1:100-1:500
- 
                                            限制
- 仅限研究用
 
- 
                                            
- 
    - 
                                            状态
- Liquid
- 
                                            浓度
- 1 mg/mL
- 
                                            缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- 
                                            储存液
- Sodium azide
- 
                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 
                                            储存条件
- -20 °C
- 
                                            储存方法
- Store at -20 °C.Stable for 12 months from date of receipt
- 
                                            有效期
- 12 months
 
- 
                                            
- 
    - GNL3L (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar)-Like (GNL3L))
- 
                                            别名
- GNL3L
- 
                                            背景
- 
                        Description: Stabilizes TERF1 telomeric association by preventing TERF1 recruitment by PML. Stabilizes TERF1 protein by preventing its ubiquitination and hence proteasomal degradation. Does so by interfering with TERF1-binding to FBXO4 E3 ubiquitin-protein ligase. Required for cell proliferation. By stabilizing TRF1 protein during mitosis, promotes metaphase-to-anaphase transition. Stabilizes MDM2 protein by preventing its ubiquitination, and hence proteasomal degradation. By acting on MDM2, may affect TP53 activity. Required for normal processing of ribosomal pre-rRNA. Binds GTP. Gene: GNL3L 
- 
                                            分子量
- 66 kDa
- 
                                            基因ID
- 54552
- 
                                            UniProt
- Q9NVN8
 抗原
- 
                    
 
                                     
                                     
                                    