Glucagon Receptor 抗体 (Internal Region)
Quick Overview for Glucagon Receptor 抗体 (Internal Region) (ABIN6258919)
抗原
See all Glucagon Receptor (GCGR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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特异性
- GLR Antibody detects endogenous levels of total GLR.
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预测反应
- Pig,Bovine,Horse,Dog
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纯化方法
- The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
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免疫原
- A synthesized peptide derived from human GLR, corresponding to a region within the internal amino acids.
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亚型
- IgG
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anti-Glucagon Receptor (GCGR) (AA 11-110) antibody
GCGR 适用: 人, 大鼠, 小鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glucagon Receptor (GCGR) (AA 26-136) antibodyGCGR 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glucagon Receptor (GCGR) (AA 1-140) antibodyGCGR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Glucagon Receptor (GCGR) (N-Term) antibodyGCGR 适用: 人, Cow, 猴, 犬, Hamster, 马 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glucagon Receptor (GCGR) (Extracellular Domain) antibodyGCGR 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glucagon Receptor (GCGR) (N-Term) antibodyGCGR 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Glucagon Receptor (GCGR) antibodyGCGR 适用: 人 IF, BR 宿主: 小鼠 Monoclonal hGR-2 F6 unconjugated Recombinant Antibody
anti-Glucagon Receptor (GCGR) (AA 200-212), (Extracellular) antibodyGCGR 适用: 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20 °C. Stable for 12 months from date of receipt.
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有效期
- 12 months
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- Glucagon Receptor (GCGR)
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别名
- GCGR
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背景
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Description: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.
Gene: GCGR
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分子量
- 54 kDa
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基因ID
- 2642
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UniProt
- P47871
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途径
- Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
抗原
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