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RGS7 抗体 (Internal Region)

This anti-RGS7 antibody is a 兔 多克隆 antibody detecting RGS7 in WB, ELISA, ICC 和 IF. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6258913
发货至: 中国

Quick Overview for RGS7 抗体 (Internal Region) (ABIN6258913)

抗原

See all RGS7 抗体
RGS7 (Regulator of G-Protein Signaling 7 (RGS7))

适用

  • 40
  • 16
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  • 3
  • 1
人, 小鼠, 大鼠

宿主

  • 38
  • 4

克隆类型

  • 40
  • 2
多克隆

标记

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  • 3
  • 3
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This RGS7 antibody is un-conjugated

应用范围

  • 28
  • 17
  • 16
  • 6
  • 3
  • 3
  • 3
  • 2
  • 1
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF)
  • 抗原表位

    • 8
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Internal Region

    特异性

    RGS7 Antibody detects endogenous levels of total RGS7.

    预测反应

    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken

    纯化方法

    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).

    免疫原

    A synthesized peptide derived from human RGS7, corresponding to a region within the internal amino acids.

    亚型

    IgG
  • 应用备注

    WB 1:500-1:1000, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20 °C. Stable for 12 months from date of receipt.

    有效期

    12 months
  • 抗原

    RGS7 (Regulator of G-Protein Signaling 7 (RGS7))

    别名

    RGS7

    背景

    Description: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:10521509, PubMed:10862767). The RGS7/GNB5 dimer enhances GNAO1 GTPase activity (PubMed:10521509). May play a role in synaptic vesicle exocytosis (PubMed:12659861). Modulates the activity of potassium channels that are activated by GNAO1 in response to muscarinic acetylcholine receptor M2/CHRM2 signaling (PubMed:15897264).

    Gene: RGS7

    分子量

    65 kDa

    基因ID

    6000

    UniProt

    P49802

    途径

    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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